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1.learn 3D printer background and find new reseach or application

The rise of 3D printing technology in the biomedical field

Background

1. The demand for personalized medicine is growing, and traditional medical solutions are difficult to meet individual differences. 3D printing can customize accurately adapted products and solutions.

2. The development of medical imaging, such as CT and MRI, can provide high-precision anatomical data for 3D printing and facilitate the creation of accurate models.

3. Innovation in material science, new biocompatible and degradable materials support the printing of devices and stents that better meet the requirements of the human body.

4. Progress in bioengineering and cell biology research to provide theoretical basis and possibility for printing tissues and organs.

5. Society's rising expectations for medical quality have prompted the industry to explore innovative technologies to improve outcomes and quality.

Multidisciplinary collaborative development and medical needs have jointly promoted the application and research of 3D printing in the biomedical field.

3D printing technology in the field of biomedical applications

• Medical models and surgical planning:

3D printing technology can be used to create patient-specific anatomical models to help doctors with surgical planning and simulation, improving the accuracy and success rate of surgery.

• Implants and prosthetics:

3D printing can make personalized implants and prostheses, such as orthopedic implants, dental restorations, etc., to better fit the patient's anatomy.

• Tissue Engineering and organ printing:

The technology can be used to build tissue engineering scaffolds that provide an environment for cells to grow and differentiate, promoting tissue regeneration. In addition, scientists are also working to explore the possibility of 3D printing organs.

• Drug development:

3D printing can be used to create drug dosage forms, such as controlled release tablets or microspheres, to enable personalized drug therapy.

• Medical devices and tools:

3D printing can be used to manufacture various medical devices and tools, such as surgical instruments, prosthetics, etc., to improve their performance and applicability.

Specific application cases of 3D printing technology in the biomedical field:

• 3D printed organs:

On March 26, 2023, a research team from the Catholic University of Korea successfully implanted the world's first 3D bioprinted artificial trachea into a patient, customized using another person's adult stem cells. The team performed the transplant on a woman in her 50s who had lost part of her windpipe after undergoing surgery for thyroid cancer. The operation took place in August last year, and after six months of follow-up observation, it was confirmed that the trachea was successfully implanted.

• 3D printed bones:

Through the 3D printer can be printed to replace the human bone titanium "bone", compared with the traditional metal bone, 3D printed "bone" not only the size is very accurate, but also with the pores for bone growth, adjacent bones will enter the pores during the growth process, so that the real bone and false bone firmly formed a body, so that the patient's recovery period is shortened.

Standardization of 3d printing in the medical field

China's Medical Device Production supervision and Management Measures list the safety and effectiveness of medical devices as the primary requirements. Currently, the U.S. Food and Drug Administration (FDA) relies primarily on sound decisions and valid scientific evidence to control risks and ensure that medical products can be used safely and effectively to improve public health. For new medical devices in the field of additive manufacturing, the corresponding regulatory science needs to be established to verify the performance of registered products. Important tasks to be completed before registration include conducting multi-center clinical trials and medical studies, as well as producing products that have been summarized and peer-reviewed and published through scientific publications to provide an important basis for clinical practice. This type of research and production will facilitate the development of innovative products and facilitate the monitoring of the entire use process during the clinical application of the product.

Metal 3D printing materials:

such as titanium, stainless steel and aluminum alloys, are used to manufacture high-strength, high-temperature and corrosion-resistant metal parts.

Composite materials:

Markforged

The characteristics of continuous carbon fiber Markforged include:

High strength and high stiffness: The addition of carbon fiber significantly improves the mechanical properties of the printed components.

Lightweight: While ensuring strength, it reduces the weight of the components.

High precision: It is capable of achieving fine and complex geometric shapes.

High precision: It is capable of achieving fine and complex geometric shapes.

Markforged has the following significant application values:

In the aerospace field, there are extremely strict requirements for the performance, weight, and reliability of components. The 3D printing continuous carbon fiber Markforged technology can manufacture components with complex shapes and high strength and lightweight characteristics, which is crucial for improving the performance and fuel efficiency of aircraft. For example, internal structural components of aircraft, such as brackets and connectors, can be custom-produced through this technology. Compared to traditional manufacturing methods, it not only reduces material waste but also optimizes the structural design of components, enabling them to maintain a relatively light weight while withstanding high-intensity loads. In addition, engine components of aircraft can also benefit from this technology. Through 3D printing continuous carbon fiber, components with good heat resistance and high strength, such as turbine blades and fan blades, can be manufactured, thereby improving the working efficiency and reliability of the engine. In the aspect of spacecraft, lightweight is one of the key factors. 3D printing continuous carbon fiber can manufacture components with high strength and lightweight that meet the requirements of the space environment, such as the structural framework and antenna brackets of satellites, helping to reduce launch costs and improve the overall performance and service life of spacecraft. Overall, the 3D printing continuous carbon fiber Markforged technology brings innovative manufacturing solutions to the aerospace field and helps promote technological development and performance improvement in this field.

Machine background

1980s: During this period, 3D printing technology began to take off. Early 3D printers used photocuring technology, which uses ultraviolet light to cure liquid photosensitive materials to stack objects layer by layer.

1990s: With the development of technology, more 3D printing technology appeared. For example, selective laser sintering (SLS) technology uses a laser beam to burn a powder material into a solid object. In addition, inkjet printing technology has also emerged, which can be printed using a variety of materials.

2000s: 3D printing technology is widely used. Traditional 3D printing technology is maturing, while new technologies such as multi-beam laser sintering (MJF) and electron beam melting (EBM) have emerged, which improve printing speed and quality.

In recent years: 3D printing technology has received greater breakthroughs and innovations. For example, bioprinting technology has emerged, which can print tissues, organs and other biomedical applications; Metal 3D printing technology has also been rapidly developed, can print complex metal parts; At the same time, multi-material printing and multi-color printing have also become a reality.

New 3D printing paper material:

In addition to traditional plastic materials, some new 3D printing paper materials have emerged in recent years. For example, the biodegradable PLA material (polylactic acid) is widely used in environmental protection and medical fields. In addition, carbon nanotube reinforced plastic materials and metal nanoparticle reinforced resin materials have also made significant progress in improving print quality and performance.

2.Use slice software to setting parameter

Set the parameters

3.Use 3D printer to manufacture it

4.Postprocess the surface

5. Try to read gcode

G1 F4800 X91.766 Y90.842 E211.66853

"G1" usually represents the linear interpolation instruction, meaning that it will move to the specified position in a straight line manner.

"F4800" indicates the feed rate is 4800 (the specific unit depends on the settings of the machine tool, and the common one might be millimeters per minute).

"X91.766 Y90.842" means to move to the position where the X-axis coordinate is 91.766 and the Y-axis coordinate is 90.842.

"E211.66853" might be related to the extrusion amount or other specific parameters. The specific meaning depends on the equipment and process to which this G-code is applied.

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